Publications Considered To Represent the Best Evidence Of Hyperbaric Medicine

Last updated May 2010

  1. Basic science
  2. Clinical Science
  3. Review

1. Air or Gas Embolism

  1. Cerebral Air Embolism Treated by Pressure and Hyperbaric Oxygen  
    Catron PW, Dutka AJ, Biondi DA, et al.
    Neurology 1991;41:314-315
  2. Pulmonary Barotrauma in Submarine Escape Trainees and the Treatment of Cerebral Arterial Air Embolism  
    Brooks GJ, Green RD, Leitch Dr.
    Aviation, Space, and Environmental Medicine 1986;57:1201-1207
  3. Pulmonary Barotrauma-Induced Cerebral Arterial Gas Embolism with Spontaneous Recovery: Commentary on the Rationale for Therapeutic Compression  
    Clarke D, Gerard W, Norris T
    Aviat Space Environ Med 2002;73(2):139-146

2. Carbon Monoxide

  1. Functional Inhibition of Leukocyte B2 Integrins by Hyperbaric Oxygen in Carbon Monoxide-Mediated Brain Injury in Rats
    Thom SR
    Toxicology and Applied Pharmacology1993;123:248-256
  2. Hyperbaric Oxygen for Acute Carbon Monoxide Poisoning  
    Weaver LK, Hopkins RO, Chan KJ, et al.
    N Engl J Med 2002;347(14):1057-1067
  3. Hyperbaric Oxygen for Carbon Monoxide Poisoning (Review Article)
    Juurlink DN, Buckley NA, Stanbrok MB, et al.
    The Cochrane Database of Systematic Reviews 2005, Issue 1. Art No: CD002041.Pub2. DOI:10.1002/14651858.CD002041.Pub2
    Carbon Monoxide Poisoning
    Piantadosi CA
    Undersea Hyper Med 2004; 31(1):167-177

3. Gas Gangrene

  1. Effect of Hyperbaric Oxygen and Surgery on Experimental Multimicrobial Gas Gangrene
    Hirn M, Niinikoski J, Lehtonen OP
    Eur Surg Res 1993;25:265-269
  2. Management of Clostridial Gas Gangrene and the Role of Hyperbaric Oxygen  
    Korhonen K, Klossner J, Hirn M, et al.
    Annales Chirurgiae ET Gynaecologiae 1999;88:139-142
  3. Clostridial Myositis, Necrotizing Fasciitis, and Zygomycotic Infections
    Jacoby I
    In: Physiology and Medicine of Hyperbaric Oxygen Therapy. Saunders Publishers. Neuman & Thom 2008:397-418

4. Crush Injury; Compartment Ischemia; Other Acute Ischemias

  1. Delayed Use of Hyperbaric Oxygen for Treatment of a Model Anterior Compartment Syndrome
    Strauss MB, Hargens AR, Gershuni DH, et al.
    Journal of Orthopaedic Research 1986;4:108-111
    Lipid Peroxidation Products in Postischemic Skeletal Muscle and After Treatment with Hyperbaric Oxygen  
    Nylander G, Otamiri T, Lewis DH, et al.
    Scandinavian Journal of Plastic Reconstructive Surgery 1989;23:97-103
  2. Hyperbaric Oxygen Therapy in the Management of Crush Injuries: A Randomized Double-Blind Placebo-Controlled Clinical Trial
    Bouachour G, Cronier P, Gouello JP, et al.
    The Journal of Trauma: Injury, Infection, and Critical Care 1996;41(2):333-339
  3. Adjuvant Hyperbaric Oxygen Therapy in the Management of Crush Injury and Traumatic Ischemia: An Evidence-Based Approach
    Garcia-Covarrubias L, McSwain N, Van Meter K, Bell R 
    The American Surgeon 2005;71(2):144-151

5. Decompression Sickness

  1. Acute Neurologic Decompression Illness in Pigs: Lesions of the Spinal Cord and Brain
    Dick EJ, Broome JU, Hayward IJ
    Laboratory Animal Science 1997;47(1):50-57
    Oxygen in the Treatments of Spinal Cord Decompression
    Leitch DR, Hallenbeck JM
    Undersea Biomedical Research 1985;12(3):269-289
  2. Twenty Years of Treating Decompression Sickness
    Green RD, Leitch DR
    Aviation, Space, and Environmental Medicine 1987:362-366
    Spinal Cord Decompression Sickness in Sport Diving
    Aharon-Peretz J, Adir Y, Gordon CR, et al.
    Arch Neurol 1993;50:753-756
  3. Bubble Trouble: A Review of Diving Physiology and Disease  
    Levett DZH, Millar IL
    Postgraduate Medical Journal 2008; 84:571-578

6. Wound Healing

  1. Diabetic Impairments in No-Mediated Endothelial Progenitor Cell Mobilization and Homing are reversed by Hyperoxia and SDF-1a
    Gallagher KA, Zhao-Jun L, et al.
    J. Clin. Invest. 2007; 117:1249-1259
    Stem Cell Mobilization by Hyperbaric Oxygen  
    Thom SR, Bhopale VM, et al.
    AM J Physiol Heart Circ Physiol 2006; 290:H1378-H1386
    Hyperbaric Oxygen Induces VEGF Expression Through ERK, JNK and C-JUN/AP-1 Activation in Human Umbilical Vein Endothelial Cells
    Lee CC, Chen SC, TSAI SC, et al.
    J Biomed SCI 2006;13(1):143-56
    Hyperbaric Oxygen Selectively Induces Angiopoietin-2 in Human Umbilical Vein Endothelial Cells  
    Lin S, Shyu KG, Lee CC, et al.
    Biochem and Biophys Research Communications  2002;296:710-715
  2. Hyperbaric Oxygen Therapy Facilitates Healing of Chronic Foot Ulcers in Patients with Diabetes
    Londahl M, Katzman P, Nilsson A, et al.
    Diabetes Care 2010;33(5):998-1003
  1. Systematic Review of Hyperbaric Oxygen in the Management of Chronic Wounds
    Roeckl-Wiedmann I, Bennett M, Kranke P
    British Journal of Surgery 2005;92:24-32
    Cost-Effectiveness and Budget Impact of Adjunctive Hyperbaric Oxygen Therapy for Diabetic Foot Ulcers
    Chuck AW, Hailey D, Jacobs P, et al.
    Intl. J. of Technology Assessment in Health Care 2008; 24(2):178-183

7. Exceptional Anemia

  1. Hyperbaric Oxygen Treatment Attenuates Cytokine Induction after Massive Hemorrhage  
    Yamashita M
    Am J Physiol Endocrinol Metab 2000;278(5):E811-E816
  2. Hyperbaric Oxygen Reverses Organ Dysfunction in Severe Anemia  
    Greensmith JE 
    Anesthesiology 2000;93(4):1149-1152
  3. A Systematic Review of the Application of Hyperbaric Oxygen in the Treatment of Severe Anemia: An Evidence-Based Approach
    Van Meter KW
    Undersea and Hyperbaric Medical Society 2005;32(1):61-83

8. Intracranial Abscess

  1. None
  2. Hyperbaric Oxygen in Intracranial Abscesses
    Lampl LA, Frey G, Dietze T, et al.
    Journal of Hyperbaric Medicine 1989;4(4):111-125
  3. Hyperbaric Oxygen in Intracranial Abscesses
    Lampl LA, Frey G, Dietze T, et al.
    Journal of Hyperbaric Medicine 1989;4(4):111-125

9. Necrotizing Soft Tissue Infections

  1. Hyperbaric Oxygen in the Treatment of Gas Gangrene and Perineal Necrotizing Fasciitis
    Hirn M
  2. Fournier’s Gangrene: Therapeutic Impact of Hyperbaric Oxygen
    Hollabaugh RS, Dmochowski RR, Hickerson WL, et al.  
    Plastic and Reconstructive Surgery 1998;101:94-100
  3. Hyperbaric Oxygen in the Treatment of Gas Gangrene and Perineal Necrotizing Fasciitis
    Hirn M
    European Journal of Surgery Supplement 1993;570:1-36

10. Refractory Osteomyelitis

  1. Synergy of HBO2 and a Local Antibiotic Carrier for Experimental Osteomyelitis Due to Staphylococcus Aureus in Rats
    Mendel V, Simanowski J, Scholz CH
    UHM 2004; 31(4):407-416
  2. Results of Chronic Osteomyelitis of the Femur Treated with Hyperbaric Oxygen: A Preliminary Report
    Chen CE, Ko JY, Fu TH, et al.
    Chang Gung Med J 2004;27(2):91-97
  3. Hyperbaric Oxygen Therapy in Chronic Osteomyelitis
    Niinikoski J
    In: Physiology and Medicine of Hyperbaric Oxygen Therapy. Saunders Publishers. Neuman & Thom 2008:419-426

11. Late Radiation Injury

  1. Relationship of Oxygen Dose to Angiogenesis Induction in Irradiated Tissue
    Marx RE, Ehler WJ, Tayapongsak P, et al.
    The American Journal of Surgery 1990;160:519-524
  2. Hyperbaric Oxygen Treatment of Chronic Refractory Radiation Proctitis: A Randomized and Controlled Double-Blind Crossover Trial with Long-Term Follow-Up.
    Clarke RE, Tenorio LMC, Hussey JR, et al.
    International Journal of Radiation Oncology, Biology, Physics 2008;72(1):134-143
  3. Hyperbaric Oxygen Therapy in the Treatment of Radio-Induced Lesions in Normal Tissues: A Literature Review
    Pasquier D, Hoelscher T, Schmutz J, et al.
    Radiology and Oncology 2004;72:1-13

12. Skin Grafts and Flaps

  1. Survival of Normothermic Microvascular Flaps After Prolonged Secondary Ischemia: Effects of Hyperbaric Oxygen  
    Stevens DM, Weiss DW, Koller WA, et al.
    Otolaryngology-Head and Neck 1996;115(4):360-364
  2. Clinical Experience with Hyperbaric Oxygen Therapy in the Salvage of Ischemic Skin Flaps and Grafts
    Bowersox JC, Strauss MB, Hart GB
    Journal of Hyperbaric Medicine 1986;1(3):141-149
  3. An Evidence-Based Appraisal of the Use of Hyperbaric Oxygen on Flaps and Grafts  
    Friedman HI, Fitzmaurice M, Clarke D, et al.
    Plastic and Reconstructive Surgery 2006;117(7S):175S-190S

13. Thermal Burns

  1. Hyperbaric Oxygen Therapy and Piracetam Decrease the Early Extension of Deep Partial-Thickness Burns
    Germonpre P, Reper P, Vanderkelen A
    Burns 1996; 22(6):468-473
  1. The Effect of Hyperbaric Oxygen Therapy on a Burn Wound Model in Human Volunteers
    Niezgoda JA, Cianci P, Folden BW, et al.
    Plastic and Reconstructive Surgery 1997;99(6):1620-1625
  2. Hyperbaric Oxygen Therapy for Thermal Burns (Review)
    Villanueva E, Bennett MH, Wasiak J, et al.
    The Cochrane Database of Systematic Reviews, 2004, Issue 2 Art. No: CD004727. Pub2. DOI: 10.1002/14651858